Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781779 | 0.85 | ALDH1A1 (0.39) | SMN1; SMN2KDM4EALDH1A1MAPK1POLB | |
| SCHEMBL8487860 | 0.84 | KDM4E (0.30) | SMN1; SMN2KDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL4460479 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EALDH1A1MAPK1POLB | |
| SCHEMBL1712860 | 0.73 | CA1 (0.55) | ALDH1A1MAPK1CA1CA2POLB | |
| SCHEMBL11662486 | 0.73 | CA1 (0.42) | SMN1; SMN2KDM4EALDH1A1MAPK1CA1 | |
| SCHEMBL3786988 | 0.72 | ALDH1A1 (0.43) | SMN1; SMN2KDM4EALDH1A1MAPK1CA1 | |
| SCHEMBL1970573 | 0.68 | APOBEC3G (0.38) | SMN1; SMN2POLBLMNAMAPTHPGD | |
| SCHEMBL24314191 | 0.68 | L3MBTL1 (0.39) | SMN1; SMN2KDM4EALDH1A1POLBLMNA | |
| SCHEMBL8388547 | 0.67 | KDM4E (0.36) | SMN1; SMN2KDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL5378587 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742201-A1 | PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |