Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21859573 | 0.84 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL24313610 | 0.82 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1KDM4EHCRTR1HCRTR2 | |
| SCHEMBL1547887 | 0.80 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1KDM4EHCRTR1HCRTR2 | |
| SCHEMBL12129077 | 0.76 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL13696460 | 0.73 | ACHE (0.44) | L3MBTL1KDM4ELMNACYP1A2CYP2D6 | |
| SCHEMBL1405871 | 0.73 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL23251431 | 0.72 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL22366691 | 0.72 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL1618282 | 0.72 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8214668 | 0.72 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1KDM4EHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |