Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890302 | 0.76 | — | — | |
| SCHEMBL7749941 | 0.75 | ACHE (0.41) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL7749946 | 0.73 | HSD17B10 (0.41) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL9619528 | 0.73 | RAPGEF4 (0.42) | TSHRMEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL3201750 | 0.70 | ALDH1A1 (0.36) | TSHRLMNAMAPTALDH1A1CYP2C9 | |
| SCHEMBL28590124 | 0.70 | ALDH1A1 (0.33) | ALDH1A1CYP2C9KDM4E | |
| SCHEMBL5281912 | 0.69 | — | — | |
| SCHEMBL1260158 | 0.68 | MAPT (0.45) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL5277062 | 0.65 | — | — | |
| SCHEMBL991861 | 0.65 | MAPT (0.39) | TSHRMEN1KMT2AGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545564-A | EXPRESSION AND SECRETION OF BETA-UROGASTRONE | EARTH CHEMICAL COMPANY, LTD. (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0207165-B1 | POLYPEPTIDE SECRETION-CAUSING VECTOR, MICROORGANISMS TRANSFORMED BY SAID VECTOR, AND PROCESS FOR PREPARING POLYPEPTIDE USING SAID MICROORGANISMS | EARTH CHEMICAL CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |
| EP-0207165-A1 | POLYPEPTIDE SECRETION-CAUSING VECTOR, MICROORGANISMS TRANSFORMED BY SAID VECTOR, AND PROCESS FOR PREPARING POLYPEPTIDE USING SAID MICROORGANISMS | EARTH CHEMICAL CO., LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |