Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946661 | 1.00 | MAOA (0.32) | MAOAMAPTALDH1A1MEN1HPGD | |
| SCHEMBL8946657 | 1.00 | MAOA (0.32) | MAOAMAPTALDH1A1MEN1HPGD | |
| SCHEMBL8946537 | 0.85 | HTR2A (0.36) | ALDH1A1MEN1KMT2AHTR2CHTR2A | |
| SCHEMBL8946539 | 0.85 | HTR2A (0.36) | ALDH1A1MEN1KMT2AHTR2CHTR2A | |
| SCHEMBL8946545 | 0.85 | HTR2A (0.36) | ALDH1A1MEN1KMT2AHTR2CHTR2A | |
| SCHEMBL9844752 | 0.73 | HTR2A (0.34) | MAOAALDH1A1HTR2CHTR2AHTR2B | |
| SCHEMBL9844749 | 0.73 | HTR2A (0.34) | MAOAALDH1A1HTR2CHTR2AHTR2B | |
| SCHEMBL9844750 | 0.73 | HTR2A (0.34) | MAOAALDH1A1HTR2CHTR2AHTR2B | |
| SCHEMBL8946329 | 0.71 | CYP3A4 (0.35) | ALDH1A1MEN1KMT2AHTR2CHTR2A | |
| SCHEMBL8946333 | 0.71 | CYP3A4 (0.35) | ALDH1A1MEN1KMT2AHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |