Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946539 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BCYP3A4MEN1 | |
| SCHEMBL8946545 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BCYP3A4MEN1 | |
| SCHEMBL8946653 | 0.85 | MAOA (0.32) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8946657 | 0.85 | MAOA (0.32) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8946661 | 0.85 | MAOA (0.32) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8946323 | 0.85 | CYP3A4 (0.35) | HTR2AHTR2CHTR2BCYP3A4MEN1 | |
| SCHEMBL8946333 | 0.85 | CYP3A4 (0.35) | HTR2AHTR2CHTR2BCYP3A4MEN1 | |
| SCHEMBL8946329 | 0.85 | CYP3A4 (0.35) | HTR2AHTR2CHTR2BCYP3A4MEN1 | |
| SCHEMBL9844752 | 0.82 | HTR2A (0.34) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL9844749 | 0.82 | HTR2A (0.34) | HTR2AHTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |