SCHEMBL9019005

SCHEMBL9019005

CCO[C@H](CI)OCCI

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9019002 1.00 THRB (0.35) THRBLMNA
SCHEMBL6249034 0.87
SCHEMBL9366414 0.81 THRB (0.32) THRBLMNA
SCHEMBL6130690 0.81 THRB (0.32) THRBLMNA
SCHEMBL9018986 0.77
SCHEMBL1484476 0.77
SCHEMBL9019150 0.77
SCHEMBL9019024 0.73
SCHEMBL9019000 0.73
SCHEMBL4842907 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250312474-A1 ANTHRACYCLINS AND CONJUGATES THEREOF SYNAFFIX B.V. (NL) 2025-10-09 US disclosed
EP-4572798-A1 ANTHRACYCLINS AND CONJUGATES THEREOF Synaffix B.V. (NL) 2025-06-25 EP disclosed
CN-119997985-A Anthracyclines and conjugates thereof 西纳福克斯股份有限公司 2025-05-13 CN disclosed
WO-2024038065-A1 ANTHRACYCLINS AND CONJUGATES THEREOF SYNAFFIX B.V. (NL) 2024-02-22 WO disclosed
EP-0434960-B1 Chiral 1,5-diiodo-2-methoxy or benzyloxy intermediates PHARMACIA SPA (IT) 1996-09-18 EP disclosed
US-5304687-A 1-alkoxy-2,2*-diiodo-diethyl ether which reacts with doxorubicin to yield anthrocycline antibiotics FARMITALIA CARLO ERBA S.R.L. (IT) 1994-04-19 US disclosed
EP-0434960-A1 Chiral 1,5-diiodo-2-methoxy or benzyloxy intermediates PHARMACIA S.p.A. (IT) 1991-07-03 EP disclosed
WO-1991009046-A1 MORPHOLINYL DERIVATIVES OF DOXORUBICIN AND PROCESS FOR THEIR PREPARATION FARMITALIA CARLO ERBA S.R.L. (IT) 1991-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312474-A1 ANTHRACYCLINS AND CONJUGATES THEREOF ANTXR2, NCL, DUT THRB 4219/4885LMNA 641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.