SCHEMBL9019093

SCHEMBL9019093

N#CCOn1c(Cl)c(Cl)c(C#N)c1-c1ccc(Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.36
USP2 O75604 1/20 0.36
THRB P10828 1/20 0.36
MAPT P10636 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 9/20 0.33
HPGD P15428 4/20 0.33
NPSR1 Q6W5P4 3/20 0.33
RXFP1 Q9HBX9 3/20 0.33
HTT P42858 2/20 0.33
HSD17B10 Q99714 2/20 0.33
NTRK1 P04629 1/20 0.33
PIM1 P11309 1/20 0.33
ACVR1 Q04771 1/20 0.33
ALDH1A1 P00352 5/20 0.33
LMNA P02545 2/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9019080 0.85 HPGD (0.34) USP2MAPTMEN1KMT2AKDM4E
SCHEMBL9019130 0.81 USP2 (0.38) L3MBTL1USP2THRBMAPTMEN1
SCHEMBL9019103 0.81 MEN1 (0.33) L3MBTL1USP2THRBMAPTMEN1
SCHEMBL9019066 0.81 MAOB (0.33)
SCHEMBL9055243 0.75 USP2 (0.38) L3MBTL1USP2THRBMAPTMEN1
SCHEMBL9019046 0.72 L3MBTL1 (0.41) L3MBTL1USP2THRBMAPTMEN1
SCHEMBL10590178 0.72 USP2 (0.44) L3MBTL1USP2THRBMAPTMEN1
SCHEMBL10590618 0.69 KDM4E (0.36) L3MBTL1USP2THRBMAPTMEN1
SCHEMBL9019068 0.66 MAPT (0.38) MAPTSMN1; SMN2KDM4EHPGDALDH1A1
SCHEMBL9019106 0.64 MAOB (0.41) L3MBTL1USP2THRBMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434940-B1 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID CO (US) 1996-05-29 EP disclosed