SCHEMBL9019130

SCHEMBL9019130

COn1c(Cl)c(Cl)c(C#N)c1-c1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.38
THRB P10828 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 8/20 0.38
NPSR1 Q6W5P4 5/20 0.38
MAPT P10636 4/20 0.38
HPGD P15428 4/20 0.38
RXFP1 Q9HBX9 4/20 0.38
HSD17B10 Q99714 2/20 0.38
SQOR Q9Y6N5 1/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
LMNA P02545 3/20 0.38
HTT P42858 2/20 0.38
ALOX15 P16050 1/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 6/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 3/20 0.36
PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9019068 0.84 MAPT (0.38) KDM4EMAPTHPGDLMNAALOX15
SCHEMBL9019093 0.81 L3MBTL1 (0.36) USP2THRBL3MBTL1KDM4ENPSR1
SCHEMBL9019106 0.79 MAOB (0.41) USP2THRBL3MBTL1KDM4ENPSR1
SCHEMBL10590178 0.79 USP2 (0.44) USP2THRBL3MBTL1KDM4ENPSR1
SCHEMBL9019009 0.77 MAOB (0.45) USP2THRBL3MBTL1KDM4ENPSR1
SCHEMBL9019084 0.76 MAOB (0.44) USP2THRBL3MBTL1KDM4ENPSR1
SCHEMBL9019046 0.76 L3MBTL1 (0.41) USP2THRBL3MBTL1KDM4ENPSR1
SCHEMBL9019066 0.75 MAOB (0.33) MAOB
SCHEMBL10590618 0.73 KDM4E (0.36) USP2THRBL3MBTL1KDM4ENPSR1
SCHEMBL9055243 0.72 USP2 (0.38) USP2THRBL3MBTL1KDM4ENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434940-B1 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID CO (US) 1996-05-29 EP claimed
US-5102904-A N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS AMERICAN CYANAMID COMPANY (US) 1992-04-07 US claimed
EP-0434940-A2 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP claimed