SCHEMBL9019084

SCHEMBL9019084

COn1c(C#N)c(C#N)c(Br)c1-c1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.44
SQOR Q9Y6N5 1/20 0.36
KDM4E B2RXH2 5/20 0.36
ALDH1A1 P00352 4/20 0.36
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
MAPT P10636 3/20 0.35
RAB9A P51151 3/20 0.35
GRIA2 P42262 1/20 0.34
GRIA4 P48058 1/20 0.34
NPSR1 Q6W5P4 3/20 0.34
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
RXFP1 Q9HBX9 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
USP2 O75604 1/20 0.34
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.34
PPARG P37231 1/20 0.34
STAT3 P40763 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9019009 0.87 MAOB (0.45) MAOBSQORKDM4EALDH1A1KMT2A
SCHEMBL9019106 0.82 MAOB (0.41) MAOBSQORKDM4EALDH1A1KMT2A
SCHEMBL9019130 0.76 USP2 (0.38) MAOBSQORKDM4EALDH1A1KMT2A
SCHEMBL9019127 0.75 MAOB (0.43) MAOBALDH1A1MAPTLMNAHPGD
SCHEMBL9018993 0.75 MAOB (0.45) MAOBSQORKDM4EALDH1A1KMT2A
SCHEMBL9703660 0.73 AR (0.51) MAOBSQORKDM4EALDH1A1KMT2A
SCHEMBL9056656 0.72 CNR1 (0.37) MAOBKDM4EALDH1A1KMT2AMEN1
SCHEMBL9519227 0.71 GRIA2 (0.42) SQORKDM4EALDH1A1KMT2AMEN1
SCHEMBL9019128 0.70 KDM4E (0.42) SQORKDM4EALDH1A1KMT2AMEN1
SCHEMBL9019069 0.69 ALDH1A1 (0.46) MAOBSQORKDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434940-B1 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID CO (US) 1996-05-29 EP claimed
US-5102904-A N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS AMERICAN CYANAMID COMPANY (US) 1992-04-07 US claimed
EP-0434940-A2 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP claimed
EP-0434940-B1 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID CO (US) 1996-05-29 EP disclosed
US-5399716-A N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1995-03-21 US disclosed
US-5347016-A N-oxygenated arylpyrrole intermediates for insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1994-09-13 US disclosed
US-5232979-A Insecticides, miticides, nematocides AMERICAN CYANAMID COMPANY (US) 1993-08-03 US disclosed
US-5102904-A N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS AMERICAN CYANAMID COMPANY (US) 1992-04-07 US disclosed