Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30760641 | 1.00 | TSHR (0.30) | TSHR | |
| SCHEMBL9019210 | 1.00 | TSHR (0.30) | TSHR | |
| SCHEMBL17583244 | 0.86 | TSHR (0.30) | TSHR | |
| SCHEMBL4904318 | 0.79 | TSHR (0.39) | TSHR | |
| SCHEMBL9238797 | 0.79 | TSHR (0.41) | TSHR | |
| SCHEMBL5709953 | 0.78 | LMNA (0.39) | TSHR | |
| SCHEMBL7159454 | 0.76 | TSHR (0.37) | TSHR | |
| SCHEMBL7161753 | 0.76 | TSHR (0.37) | TSHR | |
| SCHEMBL17789995 | 0.75 | ALDH1A1 (0.32) | TSHR | |
| SCHEMBL9019061 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434960-B1 | Chiral 1,5-diiodo-2-methoxy or benzyloxy intermediates | PHARMACIA SPA (IT) | 1996-09-18 | — | — | EP | disclosed |
| US-5304687-A | 1-alkoxy-2,2*-diiodo-diethyl ether which reacts with doxorubicin to yield anthrocycline antibiotics | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-04-19 | — | — | US | disclosed |
| EP-0434960-A1 | Chiral 1,5-diiodo-2-methoxy or benzyloxy intermediates | PHARMACIA S.p.A. (IT) | 1991-07-03 | — | — | EP | disclosed |