SCHEMBL8087997

SCHEMBL8087997

CN(C)N=C(c1ccccc1)c1ccc(N(C)C)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.70
HPGD P15428 4/20 0.70
GFER P55789 1/20 0.70
RAB9A P51151 7/20 0.58
KMT2A Q03164 6/20 0.58
NPC1 O15118 5/20 0.58
MEN1 O00255 3/20 0.58
MAPK1 P28482 3/20 0.47
TSHR P16473 2/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MAPT P10636 7/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
LMNA P02545 1/20 0.45
KCNK3 O14649 1/20 0.45
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
HBB P68871 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22203774 0.92 ALDH1A1 (0.57) ALDH1A1HPGDGFERRAB9AKMT2A
SCHEMBL10498731 0.88 ALDH1A1 (0.50) ALDH1A1HPGDGFERRAB9AKMT2A
SCHEMBL24851242 0.81 RAB9A (0.69) ALDH1A1HPGDGFERRAB9AKMT2A
SCHEMBL5339984 0.77 RAB9A (0.69) ALDH1A1HPGDGFERRAB9AKMT2A
SCHEMBL9019258 0.77 ALDH1A1 (0.65) ALDH1A1HPGDGFERRAB9AKMT2A
SCHEMBL9701745 0.75 RAB9A (0.67) ALDH1A1HPGDGFERRAB9AKMT2A
SCHEMBL22203778 0.75 CA2 (0.56) ALDH1A1HPGDGFERRAB9AKMT2A
SCHEMBL10523673 0.74 ALDH1A1 (0.72) ALDH1A1HPGDGFERRAB9AKMT2A
SCHEMBL28027772 0.74 RAB9A (0.55) ALDH1A1HPGDGFERRAB9AKMT2A
SCHEMBL4140401 0.74 RAB9A (1.00) ALDH1A1HPGDGFERRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1063103-A2 Electrolytic treatment method FUJI PHOTO FILM CO., LTD. (JP) 2000-12-27 EP disclosed