Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130345 | 0.84 | ALDH1A1 (0.40) | SMN1; SMN2MAPTSMYD3L3MBTL1ALDH1A1 | |
| SCHEMBL9795527 | 0.84 | SMYD3 (0.44) | SMYD3L3MBTL1ALDH1A1 | |
| SCHEMBL9497857 | 0.84 | SMYD3 (0.44) | SMYD3L3MBTL1ALDH1A1 | |
| SCHEMBL9497980 | 0.84 | SMYD3 (0.44) | SMYD3L3MBTL1ALDH1A1 | |
| SCHEMBL9126469 | 0.82 | SMYD3 (0.39) | SMN1; SMN2MAPTSMYD3HDAC3HDAC1 | |
| SCHEMBL9125633 | 0.80 | ALDH1A1 (0.39) | SMN1; SMN2MAPTSMYD3HDAC3HDAC1 | |
| SCHEMBL9019581 | 0.80 | ALDH1A1 (0.39) | SMN1; SMN2MAPTSMYD3L3MBTL1ALDH1A1 | |
| SCHEMBL9127102 | 0.80 | ALDH1A1 (0.39) | SMN1; SMN2MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9795195 | 0.80 | ALDH1A1 (0.39) | SMN1; SMN2MAPTSMYD3L3MBTL1ALDH1A1 | |
| SCHEMBL9498706 | 0.80 | SMYD3 (0.37) | SMN1; SMN2MAPTSMYD3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515420-B1 | NITRIC ACID ESTERS OF CYCLOHEXANOL DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-12 | — | — | EP | claimed |
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | claimed |
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |