SCHEMBL9497980

SCHEMBL9497980

NCCC(=O)N[C@H]1CC[C@H](O[N+](=O)[O-])CC1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 19/20 0.44
ALDH1A1 P00352 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9497857 1.00 SMYD3 (0.44) SMYD3ALDH1A1L3MBTL1
SCHEMBL9795527 1.00 SMYD3 (0.44) SMYD3ALDH1A1L3MBTL1
Fumaric Acid SCHEMBL9795178 0.92 SMYD3 (0.41) SMYD3
SCHEMBL9795195 0.88 ALDH1A1 (0.39) SMYD3ALDH1A1L3MBTL1
SCHEMBL9126469 0.87 SMYD3 (0.39) SMYD3ALDH1A1L3MBTL1
SCHEMBL9019562 0.84 SMN1; SMN2 (0.45) SMYD3ALDH1A1L3MBTL1
SCHEMBL9130345 0.83 ALDH1A1 (0.40) SMYD3ALDH1A1L3MBTL1
SCHEMBL9019581 0.81 ALDH1A1 (0.39) SMYD3ALDH1A1L3MBTL1
SCHEMBL9125633 0.81 ALDH1A1 (0.39) SMYD3ALDH1A1L3MBTL1
SCHEMBL9127102 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0367019-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS Roche Diagnostics GmbH (DE) 1993-05-12 EP disclosed
EP-0367019-A1 Pharmaceutical compositions containing nitroxyalkyl amine with an amide function, and method for the preparation of the compounds Roche Diagnostics GmbH (DE) 1990-05-09 EP disclosed