Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATF4 | P18848 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125633 | 0.85 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2BCHEGSR | |
| SCHEMBL9795195 | 0.85 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2BCHEGSR | |
| SCHEMBL9127102 | 0.85 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2BCHEGSR | |
| SCHEMBL9019581 | 0.85 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2BCHEGSR | |
| SCHEMBL9019562 | 0.84 | SMN1; SMN2 (0.45) | ALDH1A1L3MBTL1SMN1; SMN2BCHEMAPT | |
| SCHEMBL9795527 | 0.83 | SMYD3 (0.44) | ALDH1A1L3MBTL1SMYD3 | |
| SCHEMBL9497980 | 0.83 | SMYD3 (0.44) | ALDH1A1L3MBTL1SMYD3 | |
| SCHEMBL9497857 | 0.83 | SMYD3 (0.44) | ALDH1A1L3MBTL1SMYD3 | |
| SCHEMBL9127883 | 0.81 | KMT2A (0.56) | ALDH1A1L3MBTL1SMN1; SMN2BCHETMEM97 | |
| SCHEMBL9127645 | 0.81 | MAPT (0.38) | ALDH1A1L3MBTL1SMN1; SMN2BCHENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |