Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620994 | 0.78 | FAAH (0.39) | FAAHPHGDHMGLLHPGDALDH1A1 | |
| SCHEMBL2655759 | 0.77 | — | — | |
| SCHEMBL6662564 | 0.76 | HPGD (0.41) | FAAHPHGDHMGLLHPGDALDH1A1 | |
| SCHEMBL372524 | 0.76 | KMT2A (0.40) | FAAHPHGDHMGLLHPGDALDH1A1 | |
| SCHEMBL2655896 | 0.75 | ALDH1A1 (0.48) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10178557 | 0.73 | TRPV1 (0.43) | FAAHPHGDHMGLLHPGDALDH1A1 | |
| SCHEMBL28340251 | 0.73 | TRPV1 (0.43) | FAAHPHGDHMGLLHPGDALDH1A1 | |
| SCHEMBL21872345 | 0.73 | TRPV1 (0.40) | FAAHPHGDHMGLLHPGDALDH1A1 | |
| SCHEMBL2655370 | 0.71 | SMN1; SMN2 (0.48) | ALDH1A1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2655926 | 0.71 | CYP1A2 (0.52) | PHGDHMGLLHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515420-B1 | NITRIC ACID ESTERS OF CYCLOHEXANOL DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-12 | — | — | EP | disclosed |
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |