Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.36 |
| ▸ | DPP4 | P27487 | 5/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019530 | 0.98 | ALDH1A1 (0.44) | HPGDALDH1A1HTTMMP1MMP2 | |
| SCHEMBL9019547 | 0.81 | PIK3CD (0.50) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL9019591 | 0.79 | DPP4 (0.42) | HPGDALDH1A1MEN1KMT2ADPP7 | |
| SCHEMBL9019514 | 0.79 | SMN1; SMN2 (0.50) | HPGDALDH1A1HTTMMP1MMP8 | |
| SCHEMBL3218610 | 0.79 | SMN1; SMN2 (0.50) | HPGDALDH1A1HTTMMP1MMP8 | |
| SCHEMBL1106510 | 0.79 | CHRNB2 (0.46) | HPGDALDH1A1HTTMMP1MMP2 | |
| SCHEMBL27805805 | 0.78 | MEN1 (0.46) | HPGDALDH1A1HTTMEN1KMT2A | |
| SCHEMBL25447805 | 0.77 | ALDH1A1 (0.48) | HPGDALDH1A1HTTMMP1MMP2 | |
| SCHEMBL8014381 | 0.77 | ALDH1A1 (0.48) | HPGDALDH1A1HTTMMP1MMP2 | |
| SCHEMBL21455835 | 0.77 | ALDH1A1 (0.48) | HPGDALDH1A1HTTMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515420-B1 | NITRIC ACID ESTERS OF CYCLOHEXANOL DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-12 | — | — | EP | disclosed |
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |