Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911508 | 0.82 | DPP4 (0.44) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL6945616 | 0.80 | DPP4 (0.43) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL9019588 | 0.79 | HPGD (0.42) | DPP4DPP7HPGDALDH1A1MEN1 | |
| SCHEMBL18722240 | 0.78 | DPP4 (0.50) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL28071493 | 0.78 | DPP4 (0.50) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL28071497 | 0.78 | DPP4 (0.50) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL6044953 | 0.78 | DPP7 (0.46) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL9019530 | 0.77 | ALDH1A1 (0.44) | DPP4DPP7HPGDALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL28071553 | 0.77 | DPP4 (0.49) | DPP4DPP7DPP8DPP9HPGD | |
| Hydrochloric Acid SCHEMBL28071551 | 0.77 | DPP4 (0.49) | DPP4DPP7DPP8DPP9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515420-B1 | NITRIC ACID ESTERS OF CYCLOHEXANOL DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-12 | — | — | EP | disclosed |
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |