Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019620 | 0.84 | KDM4E (0.40) | HSD11B1KMT2AALDH1A1GAATDP1 | |
| SCHEMBL9019623 | 0.78 | ALDH1A1 (0.42) | HSD11B1KMT2AALDH1A1GAATDP1 | |
| SCHEMBL8939654 | 0.78 | ALDH1A1 (0.51) | KMT2AALDH1A1GAATDP1 | |
| SCHEMBL8939701 | 0.78 | ALDH1A1 (0.51) | KMT2AALDH1A1GAATDP1 | |
| SCHEMBL8939610 | 0.78 | ALDH1A1 (0.51) | KMT2AALDH1A1GAATDP1 | |
| SCHEMBL9019625 | 0.75 | KMT2A (0.36) | HSD11B1KMT2AALDH1A1GAATDP1 | |
| SCHEMBL9522240 | 0.75 | KMT2A (0.54) | HSD11B1KMT2AALDH1A1GAATDP1 | |
| SCHEMBL8939599 | 0.72 | ALDH1A1 (0.45) | KMT2AALDH1A1GAATDP1 | |
| Hydrochloric Acid SCHEMBL9522102 | 0.72 | POLB (0.41) | KMT2AALDH1A1GAATDP1POLB | |
| SCHEMBL11351755 | 0.71 | GAA (0.53) | KMT2AALDH1A1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626369-B1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1996-09-18 | — | — | EP | disclosed |
| EP-0626369-A1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |