Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939610 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8939701 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8939658 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8939637 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8939608 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8939639 | 0.81 | KMT2A (0.54) | ALDH1A1MAPTKMT2AMEN1HTT | |
| SCHEMBL9019622 | 0.78 | HSD11B1 (0.40) | ALDH1A1KMT2AGAATDP1 | |
| SCHEMBL8939599 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KMT2AGAANPSR1LMNA | |
| SCHEMBL9123830 | 0.73 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL11351755 | 0.73 | GAA (0.53) | ALDH1A1KMT2AGAALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626369-B1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5523464-A | BONE DISORDERS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0626369-A1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |