Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019625 | 0.87 | KMT2A (0.36) | ALDH1A1CNR2KMT2AGAATDP1 | |
| SCHEMBL9019622 | 0.78 | HSD11B1 (0.40) | ALDH1A1KMT2AGAATDP1EPHX2 | |
| SCHEMBL8939701 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAKMT2AGAATDP1 | |
| SCHEMBL8939610 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAKMT2AGAATDP1 | |
| SCHEMBL8939654 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAKMT2AGAATDP1 | |
| SCHEMBL8939599 | 0.72 | ALDH1A1 (0.45) | ALDH1A1LMNACNR2KMT2AGAA | |
| SCHEMBL31143718 | 0.72 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2AEPHX2HSD11B1 | |
| SCHEMBL31143675 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAKMT2AGAATSHR | |
| SCHEMBL4066656 | 0.72 | LMNA (0.51) | ALDH1A1LMNAKMT2AGAAEPHX2 | |
| SCHEMBL31143732 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNACNR2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626369-B1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1996-09-18 | — | — | EP | disclosed |
| EP-0626369-A1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |