Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19726779 | 0.79 | MAPT (0.33) | GAAMAPTSMN1; SMN2G6PC1ALDH1A1 | |
| SCHEMBL19713073 | 0.75 | ALDH1A1 (0.34) | GAALMNAMAPTSMN1; SMN2G6PC1 | |
| SCHEMBL21772223 | 0.72 | CYP3A4 (0.37) | GAALMNAALDH1A1 | |
| SCHEMBL18015677 | 0.68 | BCL2L1 (0.41) | MAOA | |
| SCHEMBL23264525 | 0.66 | CYP2A6 (0.48) | MAOAGAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL5238902 | 0.66 | MAOA (0.48) | MAOAMAPT | |
| SCHEMBL28121136 | 0.66 | TSHR (0.35) | GAALMNAMAPTALDH1A1 | |
| SCHEMBL8876400 | 0.65 | DRD2 (0.32) | — | |
| SCHEMBL8876396 | 0.65 | DRD2 (0.32) | — | |
| SCHEMBL21202780 | 0.65 | ALDH1A1 (0.38) | MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455510-B1 | Use of 5-HT1A receptor agonist compounds for inhibiting gastric acid secretion | LILLY CO ELI (US) | 1996-11-27 | — | — | EP | disclosed |
| EP-0385658-B1 | Ring-substituted 2-amino 1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes | LILLY CO ELI (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0455510-A2 | Use of 5-HT1A receptor agonist compounds for inhibiting gastric acid secretion | ELI LILLY AND COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0385658-A1 | Ring-substituted 2-amino 1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes | ELI LILLY AND COMPANY (US) | 1990-09-05 | — | — | EP | disclosed |