Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777000 | 0.82 | ALDH1A1 (0.33) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9019861 | 0.82 | ALDH1A1 (0.34) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9019788 | 0.81 | ACACB (0.37) | LMNAHTTNPSR1TDP1KDM4E | |
| SCHEMBL9019744 | 0.81 | ALDH1A1 (0.32) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9019755 | 0.80 | ALDH1A1 (0.32) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL965011 | 0.79 | ALDH1A1 (0.46) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8777018 | 0.78 | PDE3A (0.38) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8210030 | 0.77 | ALDH1A1 (0.48) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9019839 | 0.77 | CDK1 (0.31) | — | |
| SCHEMBL8205815 | 0.75 | ALDH1A1 (0.38) | LMNAKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-B1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |