Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | MGMT | P16455 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019755 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL9019861 | 0.82 | ALDH1A1 (0.34) | — | |
| SCHEMBL9019744 | 0.81 | ALDH1A1 (0.32) | — | |
| SCHEMBL965011 | 0.79 | ALDH1A1 (0.46) | — | |
| SCHEMBL9019786 | 0.77 | LMNA (0.36) | — | |
| SCHEMBL8210030 | 0.77 | ALDH1A1 (0.48) | — | |
| SCHEMBL8205815 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL9019773 | 0.74 | PDE3A (0.39) | — | |
| SCHEMBL8777016 | 0.74 | ALDH1A1 (0.37) | — | |
| SCHEMBL8777020 | 0.74 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-B1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |