Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | NPR3 | P17342 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019807 | 0.85 | PDE3A (0.32) | LMNAHTTMEN1ALDH1A1MAPT | |
| SCHEMBL9019826 | 0.85 | ALDH1A1 (0.37) | LMNAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL9845278 | 0.84 | SYK (0.31) | MEN1KMT2A | |
| SCHEMBL9019796 | 0.83 | CYP3A4 (0.41) | LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL9022568 | 0.83 | ACHE (0.41) | ACACBLMNAHTTNPSR1TDP1 | |
| SCHEMBL9019764 | 0.80 | PDE3A (0.38) | LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL9019800 | 0.75 | BCHE (0.38) | MEN1KMT2A | |
| SCHEMBL9019831 | 0.75 | BCHE (0.38) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9845272 | 0.74 | CYP3A4 (0.35) | LMNAMEN1MAPTKMT2A | |
| SCHEMBL9845279 | 0.74 | MEN1 (0.39) | HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-B1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |