Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586002 | 0.87 | KMT2A (0.39) | KMT2ATHRBADORA3ADORA2AMEN1 | |
| SCHEMBL10653981 | 0.81 | KMT2A (0.53) | KMT2ATHRBMEN1HTTALDH1A1 | |
| SCHEMBL9019845 | 0.79 | POLB (0.40) | KMT2ATHRBADORA3ADORA2AMEN1 | |
| SCHEMBL8182271 | 0.78 | KMT2A (0.45) | KMT2ATHRBADORA3ADORA2AMEN1 | |
| SCHEMBL537673 | 0.74 | MAPK1 (0.42) | KMT2ATHRBMEN1HTTALDH1A1 | |
| SCHEMBL11738410 | 0.74 | KMT2A (0.53) | KMT2ATHRBADORA3ADORA2AMEN1 | |
| SCHEMBL26313098 | 0.73 | MAPK1 (0.33) | KMT2ATHRBMEN1GAAMAPK1 | |
| SCHEMBL10389212 | 0.72 | MAPK1 (0.41) | KMT2ATHRBMEN1HTTALDH1A1 | |
| SCHEMBL10389241 | 0.72 | MAPK1 (0.41) | KMT2ATHRBMEN1HTTALDH1A1 | |
| SCHEMBL28715240 | 0.72 | MAPK1 (0.41) | KMT2ATHRBMEN1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2196773-A | — | — | None | — | — | JP | disclosed |
| EP-0468069-B1 | Process for producing a 4,6-bis(difluoromethoxy)-2-alkylthiopyrimidine | ASAHI GLASS CO LTD (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0244359-B1 | PROCESS FOR THE PREPARATION OF PYRIMIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-07-22 | — | — | EP | disclosed |
| EP-0468069-A1 | Process for producing a 4,6-bis(difluoromethoxy)-2-alkylthiopyrimidine | ASAHI GLASS COMPANY LTD. (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-5071982-A | Process for producing a 4,6-bis(difluoromethoxy)-2-alkylthiopyrimidine | ASAHI GLASS CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| US-5064818-A | PESTICIDAL PYRIMIDINYL (THIONO) (THIO)-PHOSPHORIC (PHOSPHONIC)ACID (AMIDE) ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |
| EP-0395968-A1 | (Thiono) (thio)pyrimidyl-phosphonyl (phosphonic) ester (amid) | BAYER AG (DE) | 1990-11-07 | — | — | EP | disclosed |
| JP-H02196773-A | PRODUCTION OF 4,6-BIS(DIFLUOROMETHOXY)-2-METHYLTHIOPYRIMIDINE | KAWAGUCHI KAGAKU KOGYO KK | 1990-08-03 | — | — | JP | disclosed |
| EP-0244359-A2 | Process for the preparation of pyrimidine derivatives | CIBA-GEIGY AG (CH) | 1987-11-04 | — | — | EP | disclosed |
| US-4692524-A | HERBICIDE INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |