Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586002 | 0.87 | KMT2A (0.39) | KMT2AMEN1GAAHTTTHRB | |
| SCHEMBL23908020 | 0.84 | POLB (0.41) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL10653981 | 0.81 | KMT2A (0.53) | POLBKMT2AMEN1GAAHTT | |
| SCHEMBL9019828 | 0.79 | KMT2A (0.41) | KMT2AMEN1GAAHTTTHRB | |
| SCHEMBL991954 | 0.78 | POLB (0.44) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL25231249 | 0.77 | F2RL3 (0.35) | KMT2AMEN1GAAHTTALDH1A1 | |
| SCHEMBL9657230 | 0.75 | ALDH1A1 (0.31) | KMT2AMEN1HTTTHRBALDH1A1 | |
| SCHEMBL62021 | 0.74 | POLB (0.53) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL2387324 | 0.74 | ADORA3 (0.48) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL16044834 | 0.73 | KMT2A (0.45) | POLBKMT2AMEN1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468069-B1 | Process for producing a 4,6-bis(difluoromethoxy)-2-alkylthiopyrimidine | ASAHI GLASS CO LTD (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0244359-B1 | PROCESS FOR THE PREPARATION OF PYRIMIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-07-22 | — | — | EP | disclosed |
| EP-0468069-A1 | Process for producing a 4,6-bis(difluoromethoxy)-2-alkylthiopyrimidine | ASAHI GLASS COMPANY LTD. (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-5071982-A | Process for producing a 4,6-bis(difluoromethoxy)-2-alkylthiopyrimidine | ASAHI GLASS CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0244359-A2 | Process for the preparation of pyrimidine derivatives | CIBA-GEIGY AG (CH) | 1987-11-04 | — | — | EP | disclosed |
| US-4692524-A | HERBICIDE INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |