SCHEMBL7586002

SCHEMBL7586002

CSc1nc(OC(F)F)cc(OC(F)F)n1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
HTT P42858 2/20 0.39
THRB P10828 1/20 0.39
ALDH1A1 P00352 3/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.33
ADORA3 P0DMS8 2/20 0.33
ADORA2A P29274 2/20 0.33
TSHR P16473 3/20 0.32
LMNA P02545 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PKM P14618 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10653981 0.89 KMT2A (0.53) KMT2AMEN1HTTTHRBALDH1A1
SCHEMBL9019845 0.87 POLB (0.40) KMT2AMEN1HTTTHRBALDH1A1
SCHEMBL9019828 0.87 KMT2A (0.41) KMT2AMEN1HTTTHRBALDH1A1
SCHEMBL9657230 0.83 ALDH1A1 (0.31) KMT2AMEN1HTTTHRBALDH1A1
SCHEMBL7945405 0.77
SCHEMBL10723913 0.77 GAA (0.46) KMT2AMEN1HTTTHRBALDH1A1
SCHEMBL13012204 0.76 PDE2A (0.35) KMT2AGAA
SCHEMBL9401270 0.73 KDM4E (0.33) KDM4ELMNA
SCHEMBL5353299 0.73 LMNA (0.45) KMT2AMEN1HTTTHRBALDH1A1
SCHEMBL9343189 0.72 LMNA (0.41) KMT2AMEN1HTTTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114447428-B Nonaqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2023-12-05 CN claimed
CN-114447428-A Non-aqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2022-05-06 CN claimed
CN-114447427-A Non-aqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2022-05-06 CN claimed
JP-10087635-A None JP disclosed
JP-2196773-A None JP disclosed
CN-122039076-A Preparation method of 2-methyl sulfoxide pyrimidine derivative 石河子大学 2026-05-15 CN disclosed
CN-114447427-B Nonaqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2024-04-05 CN disclosed
CN-114447428-B Nonaqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2023-12-05 CN disclosed
CN-114447428-A Non-aqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2022-05-06 CN disclosed
CN-114447427-A Non-aqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2022-05-06 CN disclosed
EP-0820992-B1 Process for the preparation of 4,6-bis(difluoromethoxy)-pyrimidine derivatives LONZA AG (CH) 2002-03-13 EP disclosed
US-5071982-A Process for producing a 4,6-bis(difluoromethoxy)-2-alkylthiopyrimidine ASAHI GLASS CO., LTD. (JP) 1991-12-10 US disclosed
JP-H02196773-A PRODUCTION OF 4,6-BIS(DIFLUOROMETHOXY)-2-METHYLTHIOPYRIMIDINE KAWAGUCHI KAGAKU KOGYO KK 1990-08-03 JP disclosed
EP-0375617-A1 Process for the preparation of pyrimidine derivatives CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
US-4900827-A Process for the preparation of pyrimidine derivatives CIBA-GEIGY CORPORATION (US) 1990-02-13 US disclosed
EP-0158594-B1 PROCESS FOR THE PREPARATION OF FLUOROALKOXY-AMINO-PYRIMIDINES CIBA-GEIGY AG (CH) 1988-02-10 EP disclosed
EP-0244359-A2 Process for the preparation of pyrimidine derivatives CIBA-GEIGY AG (CH) 1987-11-04 EP disclosed
US-4692524-A HERBICIDE INTERMEDIATES CIBA-GEIGY CORPORATION (US) 1987-09-08 US disclosed
EP-0158594-A1 Process for the preparation of fluoroalkoxy-amino-pyrimidines CIBA-GEIGY AG (CH) 1985-10-16 EP disclosed
US-4542216-A FLUOROALKYLATION OF A THIOPYRAMIDINE CIBA GEIGY CORPORATION (US) 1985-09-17 US disclosed