SCHEMBL9019907

SCHEMBL9019907

COC(=O)c1c(S(C)(=O)=O)ccc(C=O)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.40
ALDH1A1 P00352 6/20 0.40
VCAM1 P19320 1/20 0.40
MAPT P10636 5/20 0.39
NPC1 O15118 4/20 0.39
KMT2A Q03164 3/20 0.39
NPSR1 Q6W5P4 3/20 0.39
GAA P10253 3/20 0.39
CYP3A4 P08684 2/20 0.39
PTGES O14684 1/20 0.39
PTPN1 P18031 1/20 0.39
NR4A2 P43354 1/20 0.38
POLB P06746 3/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9448464 0.78 VCAM1 (0.41) ALDH1A1VCAM1KMT2ANPSR1GAA
SCHEMBL8489212 0.77 VCAM1 (0.40) ALDH1A1VCAM1KMT2ANR4A2LMNA
SCHEMBL6617449 0.76 ERN1 (0.47) RAB9AALDH1A1MAPTNPC1KMT2A
SCHEMBL8489410 0.76 VCAM1 (0.40) RAB9AALDH1A1VCAM1MAPTNPC1
SCHEMBL9019906 0.76 VCAM1 (0.40) ALDH1A1VCAM1MAPTKMT2ANPSR1
SCHEMBL9849710 0.74 VCAM1 (0.34) RAB9AALDH1A1VCAM1MAPTNPC1
SCHEMBL4703905 0.74 CA2 (0.41) RAB9AALDH1A1VCAM1MAPTKMT2A
SCHEMBL8492422 0.72 VCAM1 (0.37) RAB9AALDH1A1VCAM1MAPTNPC1
SCHEMBL3377543 0.71 CA1 (0.57) RAB9AALDH1A1KMT2ANR4A2POLB
SCHEMBL12553159 0.71 BACE1 (0.39) RAB9AALDH1A1MAPTKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0418175-B1 Isoxazoles herbicides RHONE POULENC AGRICULTURE (GB) 1996-07-17 EP disclosed