Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489410 | 0.79 | VCAM1 (0.40) | VCAM1CA1CA2CA9CA12 | |
| SCHEMBL9448464 | 0.78 | VCAM1 (0.41) | VCAM1CA1CA2CA9CA12 | |
| SCHEMBL8489212 | 0.77 | VCAM1 (0.40) | VCAM1CA1CA2CA9CA12 | |
| SCHEMBL9019907 | 0.76 | RAB9A (0.40) | VCAM1CA1CA2CA9CA12 | |
| SCHEMBL8492422 | 0.72 | VCAM1 (0.37) | VCAM1CA1CA2CA9CA12 | |
| SCHEMBL4700846 | 0.69 | CA1 (0.45) | VCAM1CA1CA2CA9CA12 | |
| SCHEMBL9849710 | 0.69 | VCAM1 (0.34) | VCAM1ALDH1A1NR4A2NPSR1POLB | |
| SCHEMBL16825538 | 0.69 | CA1 (0.46) | VCAM1CA1CA2CA9CA12 | |
| SCHEMBL27695487 | 0.69 | VCAM1 (0.38) | VCAM1CA1CA2CA9CA12 | |
| SCHEMBL10525614 | 0.68 | VCAM1 (0.34) | VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |