SCHEMBL9020286

SCHEMBL9020286

CS(=O)(=O)OCCn1nccc1NC=O

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MMP9 P14780 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
OXTR P30559 1/20 0.31
AVPR1A P37288 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8881436 0.80
SCHEMBL8883846 0.75 GLA (0.33) LMNA
SCHEMBL9442056 0.74
SCHEMBL5496667 0.74 MAPK1 (0.30)
SCHEMBL27691810 0.74 MAPK1 (0.30)
SCHEMBL8882941 0.74 MAPK1 (0.33)
SCHEMBL13912546 0.74 MEN1 (0.37) ALDH1A1RAB9A
SCHEMBL9020029 0.71 ALDH1A1 (0.30) ALDH1A1LMNA
SCHEMBL9020337 0.70 CYP3A4 (0.51) KDM4EALDH1A1LMNARAB9A
SCHEMBL8882142 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0332156-B1 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1996-12-18 EP disclosed
US-5366970-A Cephem compounds and pharmaceutically acceptable salts thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-11-22 US disclosed
US-5173485-A Bactericides, microbiocides FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1992-12-22 US disclosed
EP-0332156-A2 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-09-13 EP disclosed