Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020355 | 0.80 | NPC1 (0.56) | CYP3A4CYP2C19LMNAALDH1A1KDM4E | |
| SCHEMBL18740023 | 0.79 | LMNA (0.41) | CYP3A4CYP2C19LMNAALDH1A1MAPT | |
| SCHEMBL4594288 | 0.78 | CYP3A4 (0.46) | CYP3A4CYP2C19LMNAALDH1A1KDM4E | |
| SCHEMBL9020029 | 0.75 | ALDH1A1 (0.30) | LMNAALDH1A1MAPTHTTHPGD | |
| SCHEMBL13766811 | 0.75 | CYP3A4 (0.41) | CYP3A4CYP2C19LMNAALDH1A1KDM4E | |
| SCHEMBL16372235 | 0.70 | HPGD (0.47) | CYP3A4CYP2C19LMNAALDH1A1KDM4E | |
| SCHEMBL9020286 | 0.70 | KDM4E (0.31) | LMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL28758100 | 0.67 | CYP3A4 (0.46) | CYP3A4CYP2C19LMNAALDH1A1KDM4E | |
| SCHEMBL28921833 | 0.67 | LMNA (0.45) | CYP3A4CYP2C19LMNAALDH1A1KDM4E | |
| SCHEMBL3510101 | 0.67 | SMN1; SMN2 (0.52) | CYP3A4CYP2C19LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332156-B1 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| US-5366970-A | Cephem compounds and pharmaceutically acceptable salts thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-22 | — | — | US | disclosed |
| US-5173485-A | Bactericides, microbiocides | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0332156-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |