Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754697 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDABCB1MCL1 | |
| SCHEMBL9020561 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDMCL1NPC1 | |
| SCHEMBL9399315 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDMCL1NPC1 | |
| SCHEMBL9847186 | 0.79 | DPP8 (0.38) | ALDH1A1MAPTHPGDABCB1LMNA | |
| SCHEMBL9847187 | 0.79 | DPP8 (0.38) | ALDH1A1MAPTHPGDABCB1LMNA | |
| SCHEMBL9142600 | 0.78 | ABCB1 (0.48) | ALDH1A1MAPTHPGDABCB1MCL1 | |
| SCHEMBL9595803 | 0.77 | ABCB1 (0.44) | ALDH1A1MAPTHPGDABCB1MCL1 | |
| SCHEMBL8107606 | 0.77 | ABCB1 (0.42) | ALDH1A1MAPTHPGDABCB1MCL1 | |
| SCHEMBL9596796 | 0.77 | ABCB1 (0.42) | ALDH1A1MAPTHPGDABCB1MCL1 | |
| SCHEMBL8107869 | 0.77 | ABCB1 (0.44) | ALDH1A1MAPTHPGDABCB1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449191-B1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5438054-A | Antibacterial agent | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0449191-A1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |