Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18474245 | 0.73 | TDP1 (0.43) | ALDH1A1HTTLMNASMN1; SMN2TDP1 | |
| SCHEMBL7868569 | 0.72 | ALDH1A1 (0.43) | ALDH1A1HTTLMNASMN1; SMN2TDP1 | |
| SCHEMBL5299443 | 0.70 | TDP1 (0.46) | ALDH1A1HTTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL7911697 | 0.69 | ALDH1A1 (0.38) | ALDH1A1HTTLMNAPOLBMAPT | |
| SCHEMBL8745509 | 0.69 | ALDH1A1 (0.59) | ALDH1A1HTTLMNAMAPTSMN1; SMN2 | |
| SCHEMBL14509390 | 0.69 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTTDP1PKM | |
| Ammonia Solution, Strong SCHEMBL28135606 | 0.69 | TDP1 (0.44) | ALDH1A1HTTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL7875117 | 0.68 | ALDH1A1 (0.42) | ALDH1A1HTTLMNAPOLBMAPT | |
| SCHEMBL13589509 | 0.67 | TDP1 (0.48) | ALDH1A1LMNASMN1; SMN2TDP1CA1 | |
| SCHEMBL16000115 | 0.66 | ALDH1A1 (0.39) | ALDH1A1HTTLMNAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |