Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868569 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HTTPKMMLNRLMNA | |
| SCHEMBL7875252 | 0.78 | CYP19A1 (0.48) | ALDH1A1HTTMAPK1LMNAPOLB | |
| SCHEMBL7875117 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HTTMLNRLMNAMAPT | |
| Hydrochloric Acid SCHEMBL7877064 | 0.77 | KMT2A (0.47) | ALDH1A1HTTMAPK1LMNAPOLB | |
| SCHEMBL9020740 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HTTPKMMAPK1LMNA | |
| SCHEMBL8446138 | 0.68 | TSHR (0.44) | ALDH1A1LMNATDP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8444370 | 0.66 | TSHR (0.43) | ALDH1A1LMNATDP1NPC1RAB9A | |
| SCHEMBL16875307 | 0.65 | RORC (0.48) | — | |
| SCHEMBL16875582 | 0.65 | RORC (0.48) | MLNR | |
| SCHEMBL15803383 | 0.65 | BCHE (0.60) | ALDH1A1MLNRLMNATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |