Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18343745 | 0.83 | GPR3 (0.32) | GPR3KMT2AMEN1POLBLMNA | |
| SCHEMBL5034116 | 0.82 | GPR3 (0.34) | GPR3KMT2APOLB | |
| SCHEMBL1044055 | 0.78 | GPR3 (0.41) | ALDH1A1GPR3KMT2AMEN1POLB | |
| SCHEMBL29953549 | 0.78 | GPR3 (0.41) | ALDH1A1GPR3KMT2AMEN1POLB | |
| SCHEMBL11783880 | 0.77 | HTR2B (0.51) | ALDH1A1HTR7HTR2BGPR3KMT2A | |
| SCHEMBL9020869 | 0.76 | PDCD1 (0.39) | — | |
| Water SCHEMBL27413384 | 0.76 | HTR2B (0.50) | ALDH1A1HTR7HTR2BGPR3KMT2A | |
| Methyl Alcohol SCHEMBL14815699 | 0.74 | ALDH1A1 (0.38) | ALDH1A1HTR7HTR2BGPR3KMT2A | |
| SCHEMBL447441 | 0.73 | MEN1 (0.35) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL358532 | 0.73 | GPR3 (0.39) | ALDH1A1HTR7HTR2BGPR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669921-A4 | PREPARATION OF 2-ARYL CARBAPENEMS VIA A BORONIC ACID COUPLING REACTION. | MERCK & CO INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0669921-A1 | PREPARATION OF 2-ARYL CARBAPENEMS VIA A BORONIC ACID COUPLING REACTION | MERCK & CO. INC. (US) | 1995-09-06 | — | — | EP | disclosed |
| US-5442057-A | Preparation of 2-aryl carbapenems via a boronic acid coupling reaction | DECAMP ANN (US) | 1995-08-15 | — | — | US | disclosed |
| US-5338875-A | Boron containing intermediates useful in the preparation of carbapenems | MERCK & CO., INC. (US) | 1994-08-16 | — | — | US | disclosed |
| WO-1994011372-A1 | PREPARATION OF 2-ARYL CARBAPENEMS VIA A BORONIC ACID COUPLING REACTION | MERCK & CO., INC. (US) | 1994-05-26 | — | — | WO | disclosed |