Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18343745 | 0.74 | GPR3 (0.32) | MEN1KMT2ALMNAPOLBTDP1 | |
| SCHEMBL9020786 | 0.73 | ALDH1A1 (0.35) | MEN1KMT2ALMNAEDNRBEDNRA | |
| SCHEMBL9863553 | 0.72 | EDNRB (0.37) | MEN1KMT2ALMNAEDNRBEDNRA | |
| SCHEMBL5034116 | 0.70 | GPR3 (0.34) | KMT2APOLB | |
| SCHEMBL1044055 | 0.70 | GPR3 (0.41) | MEN1KMT2ALMNAEDNRBEDNRA | |
| SCHEMBL29953549 | 0.70 | GPR3 (0.41) | MEN1KMT2ALMNAEDNRBEDNRA | |
| SCHEMBL9020869 | 0.68 | PDCD1 (0.39) | PDK2 | |
| SCHEMBL27659967 | 0.67 | HDAC4 (0.40) | MEN1KMT2AEDNRBEDNRAALDH1A1 | |
| SCHEMBL28139840 | 0.66 | NPC1 (0.47) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL15519390 | 0.66 | PTGS2 (0.47) | ALDH1A1ENPP1COMTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9349960-B2 | Compounds and polymers which contain substituted indenofluorene derivatives as structural unit, process for the preparation thereof, and the use thereof as electronic devices and mixtures and solutions | MERCK PATENT GMBH (DE) | 2016-05-24 | — | — | US | disclosed |
| US-20120061617-A1 | POLYMERS WHICH CONTAIN SUBSTITUTED INDENOFLUORENE DERIVATIVES AS STRUCTURAL UNIT, PROCESS FOR THE PREPARATION THEREOF, AND THE USE THEREOF | MERCK PATENT GMBH (DE) | 2012-03-15 | — | — | US | disclosed |
| WO-2010136110-A2 | POLYMERS COMPRISING SUBSTITUTED INDENOFLUORENE DERIVATES AS STRUCTURAL UNITS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120061617-A1 | POLYMERS WHICH CONTAIN SUBSTITUTED INDENOFLUORENE DERIVATIVES AS STRUCTURAL UNIT, PROCESS FOR THE PREPARATION THEREOF, AND THE USE THEREOF | PPID, PCID2, OCIAD1 | MEN1 4773/4885KMT2A 4490/4885LMNA 1722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.