Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 11/20 | 0.41 |
| ▸ | CPB1 | P15086 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875144 | 0.72 | CPB2 (0.40) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| SCHEMBL9020747 | 0.67 | TAAR1 (0.45) | HRH4 | |
| SCHEMBL9020703 | 0.67 | HPGD (0.35) | CPB2CPB1 | |
| SCHEMBL1887218 | 0.67 | CYP2C9 (0.61) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| SCHEMBL7879771 | 0.66 | CYP2C9 (0.38) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL4046577 | 0.66 | TDP1 (0.62) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| SCHEMBL22783610 | 0.65 | CYP2C9 (0.62) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| SCHEMBL15020818 | 0.64 | CPB2 (0.54) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| SCHEMBL10655199 | 0.64 | CPB2 (0.49) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| SCHEMBL589342 | 0.64 | CYP2C9 (0.60) | CPB2CPB1CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |