Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.31 |
| ▸ | CPB1 | P15086 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877324 | 0.75 | CASR (0.33) | HPGDHTTCPB2CPB1TP53 | |
| SCHEMBL9020870 | 0.67 | CPB2 (0.41) | CPB2CPB1 | |
| SCHEMBL9097894 | 0.66 | CPB2 (0.42) | CPB2CPB1 | |
| SCHEMBL13684790 | 0.63 | CPB2 (0.38) | CPB2CPB1 | |
| SCHEMBL24066843 | 0.62 | RIPK1 (0.42) | HPGDALDH1A1MAPK1LMNA | |
| SCHEMBL9020652 | 0.61 | ALDH1A1 (0.40) | HPGDHTTALDH1A1LMNATHRB | |
| SCHEMBL8284300 | 0.59 | CYP3A4 (0.39) | HTTALDH1A1 | |
| SCHEMBL8652871 | 0.59 | CASR (0.31) | ALDH1A1 | |
| SCHEMBL3406306 | 0.58 | TSHR (0.49) | HPGDHTTALDH1A1MAPK1 | |
| SCHEMBL3408208 | 0.58 | TSHR (0.49) | HPGDHTTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |