Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370707 | 0.76 | TAAR1 (0.42) | TAAR1HRH4TBXAS1TERTNAMPT | |
| SCHEMBL9021052 | 0.74 | ADRB2 (0.44) | TAAR1HRH4TBXAS1TERTADRA2C | |
| SCHEMBL21099034 | 0.72 | TERT (0.49) | TAAR1HRH4TBXAS1TERTNAMPT | |
| SCHEMBL23761758 | 0.68 | TERT (0.51) | TAAR1HRH4TBXAS1TERT | |
| SCHEMBL7875355 | 0.68 | TAAR1 (0.41) | TAAR1HTR1AHRH4TBXAS1TERT | |
| SCHEMBL21573829 | 0.67 | TERT (0.50) | TAAR1HTR1AHRH4TBXAS1TERT | |
| SCHEMBL1488117 | 0.67 | TERT (0.53) | TAAR1HTR1AHRH4TBXAS1TERT | |
| SCHEMBL27220846 | 0.66 | TERT (0.56) | TAAR1HTR1ATBXAS1TERTNAMPT | |
| SCHEMBL13896544 | 0.66 | MPO (0.61) | — | |
| SCHEMBL28937531 | 0.66 | TERT (0.49) | TAAR1HTR1AHRH4TBXAS1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |