Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | NPR3 | P17342 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021602 | 0.90 | ACHE (0.40) | BCHEACHENPR3ADORA3ADORA2A | |
| SCHEMBL9021161 | 0.89 | BCHE (0.50) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9019704 | 0.86 | NPR3 (0.40) | BCHENPR3PRKCAPRKCDTBXAS1 | |
| SCHEMBL9575361 | 0.82 | BCHE (0.48) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9021427 | 0.80 | ACHE (0.42) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9021416 | 0.80 | ACHE (0.41) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9021782 | 0.78 | ACHE (0.43) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9021299 | 0.78 | ACHE (0.42) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9021599 | 0.77 | ACHE (0.41) | BCHEACHE | |
| SCHEMBL10364108 | 0.76 | ACHE (0.40) | ACHENPR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-B1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |