Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021161 | 0.93 | BCHE (0.50) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9575342 | 0.87 | ACHE (0.43) | BCHEACHEADORA2A | |
| SCHEMBL9021299 | 0.86 | ACHE (0.42) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9845246 | 0.85 | BCHE (0.36) | BCHEACHEHPGD | |
| SCHEMBL9020901 | 0.82 | BCHE (0.48) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9575496 | 0.80 | ACHE (0.42) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9575530 | 0.80 | ACHE (0.43) | BCHEACHEADORA2A | |
| SCHEMBL9021416 | 0.79 | ACHE (0.41) | BCHEACHEADORA3ADORA2AADORA1 | |
| SCHEMBL9019800 | 0.78 | BCHE (0.38) | BCHEACHEHPGD | |
| SCHEMBL9021782 | 0.77 | ACHE (0.43) | BCHEACHEADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |