Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22431540 | 0.85 | CYP19A1 (0.59) | CYP19A1LMNAQPCT | |
| SCHEMBL9021116 | 0.85 | SIGMAR1 (0.52) | LMNASIGMAR1QPCT | |
| SCHEMBL8949393 | 0.85 | CYP1A2 (0.52) | CYP19A1LMNAQPCT | |
| SCHEMBL9373597 | 0.81 | ALDH1A1 (0.49) | CYP19A1LMNATBXAS1QPCT | |
| SCHEMBL7868767 | 0.76 | CYP19A1 (0.47) | CYP19A1HMOX1TBXAS1QPCT | |
| SCHEMBL10240737 | 0.73 | QPCT (0.61) | LMNATBXAS1QPCT | |
| SCHEMBL8445855 | 0.72 | QPCT (0.57) | CYP19A1LMNATBXAS1QPCT | |
| SCHEMBL5655551 | 0.70 | CYP19A1 (0.71) | CYP19A1HMOX1TBXAS1 | |
| SCHEMBL22431461 | 0.70 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL12045347 | 0.70 | HMOX1 (0.84) | CYP19A1HMOX1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |