Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021182 | 0.83 | LMNA (0.50) | ALDH1A1TSHRCYP11B1CYP11B2MEN1 | |
| SCHEMBL7875256 | 0.78 | TSHR (0.57) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11641434 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11641542 | 0.75 | TSHR (0.46) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL9020780 | 0.71 | CYP11B1 (0.43) | TSHRCYP11B1CYP11B2LMNACYP1A2 | |
| SCHEMBL11643874 | 0.70 | ALDH1A1 (0.51) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL9021146 | 0.69 | TP53 (0.43) | ALDH1A1TSHRCYP11B1CYP11B2LMNA | |
| SCHEMBL10959040 | 0.68 | CYP3A4 (0.54) | ALOX15TDP1KMT2ALMNACYP1A2 | |
| SCHEMBL11840642 | 0.67 | ALDH1A1 (0.50) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11643409 | 0.66 | FNTA (0.46) | ALOX15TSHRCYP11B1CYP11B2FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |