Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | PTGIR | P43119 | 4/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22958943 | 0.91 | LMNA (0.43) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL29993479 | 0.82 | MAPK1 (0.47) | TBXAS1LMNAALDH1A1 | |
| SCHEMBL29557268 | 0.77 | TBXAS1 (0.44) | TBXAS1LMNATSHRNFKB1PMP22 | |
| SCHEMBL29446289 | 0.77 | TBXAS1 (0.44) | TBXAS1LMNATSHRNFKB1PMP22 | |
| Sebacic Acid SCHEMBL27937400 | 0.71 | TSHR (0.86) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL25186232 | 0.71 | TSHR (1.00) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL596235 | 0.71 | TSHR (1.00) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL166746 | 0.71 | TSHR (1.00) | LMNATSHRNFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL20500595 | 0.71 | TSHR (1.00) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL5475921 | 0.71 | TSHR (1.00) | LMNATSHRNFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480901-B1 | Azido-substituted fatty acid analog enzyme substrates | UNIV WASHINGTON (US) | 1996-06-19 | — | — | EP | disclosed |
| US-5397701-A | Myristoylation at terminal glycines in proteins or peptides with CoA ester of the analog | WASHINGTON UNIVERSITY (US) | 1995-03-14 | — | — | US | disclosed |
| US-5338858-A | Viricides | WASHINGTON UNIVERSITY (US) | 1994-08-16 | — | — | US | disclosed |
| EP-0480901-A1 | Azido-substituted fatty acid analog enzyme substrates | WASHINGTON UNIVERSITY (US) | 1992-04-15 | — | — | EP | disclosed |