Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022813 | 0.99 | ABL1 (0.40) | BCL9CTNNB1ALDH1A1ABL1TOP2A | |
| SCHEMBL9013880 | 0.99 | ABL1 (0.40) | BCL9CTNNB1ALDH1A1ABL1TOP2A | |
| SCHEMBL8800057 | 0.81 | HRH1 (0.47) | ABL1GNAI3GNAO1GNAI1HRH1 | |
| SCHEMBL9022461 | 0.81 | TOP2A (0.35) | BCL9CTNNB1TOP2ASLC6A4HTR1A | |
| SCHEMBL9013871 | 0.80 | PDE4A (0.36) | BCL9CTNNB1TOP2ASLC6A4HTR1A | |
| SCHEMBL9022816 | 0.80 | HRH1 (0.46) | ABL1GNAI3GNAO1GNAI1CNR2 | |
| SCHEMBL9023043 | 0.80 | HRH1 (0.46) | ABL1GNAI3GNAO1GNAI1CNR2 | |
| SCHEMBL9022785 | 0.80 | HRH1 (0.46) | ABL1GNAI3GNAO1GNAI1CNR2 | |
| Hydrochloric Acid SCHEMBL9013913 | 0.79 | GNAI3 (0.46) | BCL9CTNNB1ALDH1A1TOP2AGNAI3 | |
| SCHEMBL9022423 | 0.77 | SLC6A4 (0.38) | BCL9CTNNB1TOP2ASLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | claimed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | claimed |