Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022813 | 1.00 | ABL1 (0.40) | ABL1GNAI3GNAO1GNAI1BCL9 | |
| SCHEMBL9023282 | 0.99 | BCL9 (0.39) | ABL1GNAI3GNAO1GNAI1BCL9 | |
| SCHEMBL9022785 | 0.81 | HRH1 (0.46) | ABL1GNAI3GNAO1GNAI1CNR2 | |
| SCHEMBL9022816 | 0.81 | HRH1 (0.46) | ABL1GNAI3GNAO1GNAI1CNR2 | |
| SCHEMBL9023043 | 0.81 | HRH1 (0.46) | ABL1GNAI3GNAO1GNAI1CNR2 | |
| SCHEMBL9013871 | 0.81 | PDE4A (0.36) | GNAI3GNAO1GNAI1BCL9CTNNB1 | |
| Hydrochloric Acid SCHEMBL9013913 | 0.80 | GNAI3 (0.46) | GNAI3GNAO1GNAI1BCL9CTNNB1 | |
| SCHEMBL8800057 | 0.80 | HRH1 (0.47) | ABL1GNAI3GNAO1GNAI1 | |
| SCHEMBL9022461 | 0.80 | TOP2A (0.35) | BCL9CTNNB1TOP2ASLC6A4HTR1A | |
| SCHEMBL9023177 | 0.79 | HTR1A (0.44) | GNAI3GNAO1GNAI1ESR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |