Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023281 | 0.92 | KMT2A (0.36) | MEN1USP2KMT2ASMN1; SMN2ACHE | |
| SCHEMBL9024132 | 0.86 | ALDH1A1 (0.33) | MEN1KMT2A | |
| SCHEMBL9024039 | 0.83 | NQO2 (0.43) | — | |
| SCHEMBL9024175 | 0.83 | NQO2 (0.40) | — | |
| SCHEMBL9024129 | 0.82 | ABCB1 (0.36) | MEN1USP2KMT2ASMN1; SMN2ACHE | |
| SCHEMBL9023686 | 0.80 | HTT (0.34) | MEN1KMT2A | |
| SCHEMBL8547454 | 0.79 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL9023606 | 0.78 | ALDH1A1 (0.34) | MEN1KMT2A | |
| SCHEMBL8543080 | 0.78 | MAPT (0.35) | MEN1KMT2A | |
| SCHEMBL9025537 | 0.77 | TOP2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |