Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171507 | 0.87 | OPRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1CCR1 | |
| SCHEMBL29602661 | 0.87 | OPRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1CCR1 | |
| Hydrochloric Acid SCHEMBL20744290 | 0.85 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1CCR1 | |
| Hydrochloric Acid SCHEMBL30305364 | 0.85 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1CCR1 | |
| Hydrochloric Acid SCHEMBL2224231 | 0.85 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1CCR1 | |
| Formic Acid SCHEMBL3905110 | 0.82 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OPRL1CCR1 | |
| SCHEMBL9023716 | 0.76 | TSHR (0.38) | OPRM1HSD11B1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7426632 | 0.75 | HSD11B1 (0.43) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL24455261 | 0.75 | OPRM1 (0.60) | OPRM1OPRD1OPRK1OPRL1CCR1 | |
| Hydrochloric Acid SCHEMBL8353054 | 0.74 | HSD11B1 (0.42) | OPRM1OPRD1OPRK1OPRL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463810-B1 | Heterocyclic compound and psychopharmaceutical composition containing same | SUNTORY LTD (JP) | 1996-01-10 | — | — | EP | disclosed |
| US-5158947-A | CONDENSED HETEROCYCLIC COMPOUNDS AND PSYCHOPHARMACEUTICAL COMPOSITION CONTAINING SAME | SUNTORY LIMITED (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0463810-A1 | Heterocyclic compound and psychopharmaceutical composition containing same | SUNTORY LIMITED (JP) | 1992-01-02 | — | — | EP | disclosed |