Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 5/20 | 0.38 |
| ▸ | NQO2 | P16083 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024575 | 0.88 | NQO2 (0.36) | NQO1NQO2SYKGLAHPGD | |
| SCHEMBL9024703 | 0.86 | NQO2 (0.48) | NQO1NQO2IDO1 | |
| SCHEMBL9023722 | 0.84 | TOP2A (0.38) | NQO1NQO2SYKGLAHPGD | |
| SCHEMBL9024299 | 0.82 | NQO2 (0.49) | NQO1NQO2GRIN1GRIN2AGRIN2B | |
| SCHEMBL9024179 | 0.81 | NQO2 (0.48) | NQO1NQO2GRIN1GRIN2AGRIN2B | |
| SCHEMBL9024634 | 0.81 | MAPT (0.32) | MAPTHTT | |
| SCHEMBL9024437 | 0.81 | NQO2 (0.37) | NQO1NQO2MAPTHTTIDO1 | |
| SCHEMBL9023550 | 0.80 | G6PD (0.46) | G6PDNQO1NQO2MAPTHTT | |
| SCHEMBL8546191 | 0.80 | IDO1 (0.37) | NQO1NQO2IDO1 | |
| SCHEMBL9023814 | 0.79 | NQO2 (0.36) | NQO1NQO2MAPTHTTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |