Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NQO1 | P15559 | 5/20 | 0.35 |
| ▸ | NQO2 | P16083 | 5/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024559 | 0.87 | MAPT (0.39) | G6PDHTTMAPTLMNAMEN1 | |
| SCHEMBL9023936 | 0.86 | NQO2 (0.34) | G6PDHTTMAPTNQO1NQO2 | |
| SCHEMBL9025049 | 0.83 | G6PD (0.47) | G6PDHTTMAPTNQO1NQO2 | |
| SCHEMBL9024240 | 0.81 | KDM1A (0.38) | NQO1NQO2MEN1KMT2AMAOA | |
| SCHEMBL9025088 | 0.81 | ALDH1A1 (0.40) | NQO1NQO2GLARECQLALDH1A1 | |
| SCHEMBL9023847 | 0.80 | G6PD (0.39) | G6PDHTTMAPTNQO1NQO2 | |
| SCHEMBL9023982 | 0.79 | MAPT (0.36) | G6PDHTTMAPT | |
| SCHEMBL9024950 | 0.78 | AR (0.40) | HTTMAPTNQO1NQO2LMNA | |
| SCHEMBL9737128 | 0.76 | G6PD (0.46) | G6PDHTTMAPTNQO1NQO2 | |
| SCHEMBL9023606 | 0.69 | ALDH1A1 (0.34) | HTTMAPTNQO2KDM5AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |